From a current Medical Student as taught by Medical School Professors. You Should not mix Acetaminophen (Tylenol) and Acetylsalicylic acid (Aspirin). The reason for this is long term renal (kidney) damage. What happens in the Tylenol induces the formation of free oxide radicals which damage tissues (especially the kidneys and liver). This is normally not an issue at low Tylenol doses. However, when you add Aspirin to the mix, the free oxide radicals become an issue. Aspirin is a Cyclooxygenase inhibitor (COX), which decreases prostaglandin (PGE 2) synthesis. Prostaglandins are responsible for vasodilatation of the renal afferent arterioles. If you are on Aspirin the renal afferent arterioles are vasoconstricted and subsequently renal blood flow is decreased. When renal blood flow is compromised your kidney is less able to deal with the free oxide radicals produced by Tylenol. So what happens? The free oxide radicals damage the renal medulla (which may slough off) or lose the ability to concentrate urine due to damage to the most notably the thick ascending limb of the nephron. This is called Analgesic Nephropathy. Having said this, the damage is caused by long term mixing of Tylenol and Aspirin, so having mixed the two in the past once five years ago is not going to compromise your kidneys. Just make sure to avoid the mistake in the future, and Pass on this information (there are way too many sources providing incorrect information on this subject).

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Aspirin only works through the stomach. Chewing it will hasten it`s absorption and not a problem. Drink water after.

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I have read that when taking statins you should also take CoQ10 because of muscle waste is this true? Also is it ok to take aspirin or niacin with statins? I just started takin pravastin and want to get the full benefits of this med. No side effects as of now, taken for about a month.

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ummmm i say sodium

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i took 20-something aspirin about 12:30 yesterday afternoon. it was extremely painful. i had the worst stomach pain, i felt weak and my ears were ringing. i stayed up quite awhile and didnt go to sleep til about 3 in the morning. im awake now. i didnt throw up but my stomach still hurts a bit and the ringing in my ears got a bit louder.... i dont know why youre asking just please, please dont do it! D:

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nothing it will just be more uncomfortable

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Hi I have tried it, I have been using it for approx 2-3 weeks. I haven`t noticed much of a difference to the spider veins I already have, and I haven`t noticed an increase in circulation. I have however noticed that my legs aren`t as itchy. And I have Also been noticing more bruises showing up and I don`t usually bruise so easy. I don`t know if that has any relevance though. Have you been trying it?

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Aspirin is best in my opinion. It works well to take down fever and has been used for years without any bad side effects.

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You get sick and risk stomach damage. But like 4 aspirin, you`re fine...the point of too much takes more than tylenol.

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I dunno u can die

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